MSc Computer Science

Samuel
Selasi Kporvie

Researcher  ·  Quantitative Analyst  ·  Evidence Synthesis

MSc Computer Science graduate specialising in privacy-preserving computation and cost-effectiveness modelling for global health. Building rigorous analytical frameworks from QSAR drug-discovery pipelines to homomorphic encryption systems validated on 500,000+ real-world records.

500K+ Emails Validated
5+ Manuscripts
4× PyPI Packages
Top 5% ALX Graduate

Areas of Expertise

Three interconnected domains that define this research portfolio — each grounded in rigorous quantitative methodology and applied to real-world impact.

Quantitative Modelling

Building rigorous predictive frameworks that operate under uncertainty — from QSAR drug-discovery pipelines with probabilistic activity predictions to ML classifiers with explicit sensitivity analysis and fully auditable, reproducible workflows.

QSAR Pipelines ML Classifiers Cost-Effectiveness scikit-learn RDKit AutoDock Vina

Privacy & Security

Developing novel cryptographic systems that preserve analytical utility while achieving zero data exposure — including the HEKSM framework validated on 500,000+ Enron emails with 100% precision and recall, fully GDPR-compliant.

Homomorphic Encryption HEKSM BFV Scheme GDPR Compliance Microsoft SEAL Forensic Analytics

Global Health Evidence

Applying a biomedical engineering foundation to intervention impact analysis in low-resource settings — synthesising evidence on treatment efficacy, disease burden, and public health infrastructure across sub-Saharan Africa.

Biomedical Engineering Intervention Analysis Evidence Synthesis Sub-Saharan Africa Drug Discovery HBV / HCV

Selected Work

Open-source tools, research implementations, and public data infrastructure — all built for transparency, reproducibility, and real-world impact.

Published on PyPI

PyForensicKit

Open-source digital forensics toolkit incorporating cryptographic evidence integrity verification (MD5, SHA-1, SHA-256), timeline reconstruction, and structured reporting. Designed for transparent, auditable evidence analysis with a commitment to reproducibility.

Python Cryptography Forensics PyPI
Top 5% ALX Graduate Project

Know Afrika API

Public REST API providing structured, open data on African countries — directly relevant to global health and sub-Saharan Africa research contexts. Built as a capstone for the ALX Backend Specialisation, earning a Top 5% Graduate distinction.

REST API FastAPI PostgreSQL Docker
Published on PyPI

APIScan

Security assessment CLI tool that produces structured JSON and HTML diagnostic reports — demonstrating the ability to translate complex technical findings into clear, actionable outputs for varied audiences, including non-technical stakeholders.

Python Security CLI JSON/HTML Reports
Manuscript Under Review

CYP19A1 Inhibitor Pipeline

Integrated QSAR modelling and molecular docking pipeline to rank natural-product compounds by predicted cost-effectiveness — binding affinity, ADMET properties — with probabilistic predictions under uncertainty and explicit sensitivity analysis.

QSAR RDKit AutoDock Vina scikit-learn

Research Output

Peer-reviewed manuscripts, extended abstracts, and ongoing collaborative research across cryptography, machine learning, and computational biology.

Securing Third-Party Data in Forensic Investigations Using Homomorphic Encryption
Danso-Ansong, E., Kporvie, S.S. — Journal Manuscript, 2025
Under Review
Securing Healthcare with Deep Learning: CNN-Based IoT Threat Detection
Ngula, A. et al. (Co-Author) — Manuscript, 2025
Under Review
In Silico Identification of Natural-Product Aromatase (CYP19A1) Inhibitors
Kporvie, S.S. et al. (Co-author) — Manuscript, 2025
Under Review
LSTM-Based Framework for Insider Threat Detection in Identity Management Systems
Agaga, C. et al. (Co-author) — Manuscript, 2025
Under Review
MSc Extended Abstract & Seminar: Homomorphic Encryption-Based Keyword Search
Kporvie, S.S. — University of Ghana, Legon, 2025
Presented

Technical Stack

A research-grade toolkit spanning quantitative modelling, privacy engineering, full-stack development, and data visualisation.

Languages
Python JavaScript C C++ R (RStudio) SQL LaTeX / Bash
Frameworks
Django FastAPI Flask React Oracle Cloud Infrastructure (OCI)
Databases
PostgreSQL MySQL Oracle DB MongoDB
DevOps & VCS
Docker Kubernetes Git / GitHub GitLab
ML & Data Science
pandas / NumPy scikit-learn TensorFlow / Keras RDKit AutoDock Vina
Privacy & Security
Microsoft SEAL / Ten SEAL BFV Scheme Homomorphic Encryption GDPR Compliance Differential Privacy
Data Visualisation
Power BI Tableau RStudio
Design Tools
Figma / Adobe XD Photoshop Illustrator Draw.io Canva

Experience

Dec 2022 – Present
Webmaster & Technical Lead
FESF Foundation
Designing and maintaining organisational web infrastructure supporting programme delivery. Managing on-call incident response, producing clear technical reports for non-technical leadership, and demonstrating reliability under operational pressure.
Jun – Sep 2020
Research Assistant
WACCBIP — West African Centre for Cell Biology of Infectious Pathogens
Synthesised biomedical literature to identify candidate HBV inhibitors. Built a reproducible in silico drug discovery pipeline combining ML classifiers and molecular docking (AutoDock Vina), producing ranked compound binding affinity outputs.
AutoDock Vina Python scikit-learn
Aug 2020 – Sep 2022
Backend Developer
GI-KACE (Ghana-India Kofi Annan Centre for Excellence)
Developed a full Appraisal Management System (FastAPI + PostgreSQL) from requirements analysis through deployment. Evaluated and improved e-government applications, producing systematic assessments and targeted improvement recommendations.
FastAPI PostgreSQL Docker

Education

Sep 2025
MSc Computer Science — Distinction
University of Ghana, Legon
Thesis: Securing Third-Party Data in Forensic Investigations Using Homomorphic Encryption.

Awarded Distinction — the highest classification — recognising the rigour of research methodology and quality of written output.

Core coursework: Research Methods, Advanced Data Structures and Algorithms, Advanced Database Systems, Statistical Analysis, Machine Learning, Information Systems Security.
Oct 2020
BSc Biomedical Engineering — Second Class Honours
University of Ghana, Legon
Project: Securing ML-Based Prediction of Drug-Like Inhibitors of Hepatitis C NS5B Protein.

Biomedical engineering foundation providing direct domain knowledge in global health intervention contexts — disease burden, treatment efficacy, and healthcare systems in low-resource settings.

Credentials

Oracle Cloud Infrastructure — OCI Data Science Professional

Oracle University / Oracle Africa Region · Nov 2025 · Valid Nov 2027

OCI services for machine learning and data analytics workflows.

Data Science in Precision Medicine & Cloud Computing

Stanford Medicine, Department of Genetics · May 2025

Biomedical data analysis and cloud-based workflows for precision medicine.

Ethical Hacking: Cryptography (1 CEU/CPE)

Cybrary · April 2025

Encryption schemes, hashing, key management, and cryptography in security contexts.

Software Engineering — Top 5% Backend Specialisation Graduate

African Leadership Experience (ALX), Nairobi · December 2023

Backend-focused training in scalable systems and API development.

Systems Engineering & Networking

IPMC, North Legon · March 2017

CompTIA A+, Computer Hardware.

Available for Research Collaborations

Let's Build Rigorous
Research Together

Open to research positions, collaborative projects, and consulting engagements in quantitative analysis, global health evidence synthesis, and privacy-preserving computation.

samelsekasi@gmail.com